Chicago sees surge in foreclosure auctions









More than 35,000 homes and small multifamily buildings in the Chicago area completed the foreclosure process last year, the highest number since the housing crisis began, and the vast majority of them became bank-owned.


An increase in foreclosure auctions was expected since lenders shelved many foreclosure cases while state and federal authorities investigated allegations of faulty foreclosure processes. Still, the heightened level of auctions — 35,244 in 2012, compared with 20,281 in 2011 — along with an increase in initial foreclosure filings, shows the local housing market has a long road to recovery, according to the Woodstock Institute.


"There's going to be pain in the housing market in the short term," said Katie Buitrago, senior policy and communications associate at Woodstock. "There's still high levels of filings. Five years into it, there is still work to be done to help people save their homes."








The Chicago-based public policy and research group is expected to release its report on 2012 foreclosure activity Wednesday.


The year-end numbers show that, with few exceptions, all Chicago neighborhoods and suburban communities saw high double-digit percentage gains in auctions last year. Across the six-county area, 91.3 percent of the foreclosed properties were repossessed by lenders. At the same time, notices of initial default sent to homeowners, the first step in the foreclosure process, increased by 2.9 percent last year, to 66,783.


Real estate agents have worried for more than two years about a glut of foreclosed properties — a shadow inventory — that banks would list for sale en masse and cause home values to plunge. That largely has not happened, but the vast number of distressed properties in the market has kept a lid on local home values.


On Tuesday, for instance, Fannie Mae and Freddie Mac's websites listed 2,415 Cook County homes for sale that the two agencies had repossessed.


Chicago-area home prices, including distressed sales, fell 2.3 percent in December from a year ago, housing analytics firm CoreLogic said Tuesday. Illinois was one of only four states to see home-price depreciation.


The increase in auctions "is a mixed blessing," Buitrago said. "We've been having a lot of trouble in the region with vacant properties that have been languishing for years. The longer they're vacant, the more likely they are to be a destabilizing force in their communities."


Woodstock found that within the city of Chicago, there were 20 communities where more than 1 in 10 owner-occupied one- to four-unit residential buildings and condos went through foreclosure from 2008 to 2012. Five of those neighborhoods are included in the city's 18-month-old Micro-Market Recovery Program, a coordinated effort to stabilize neighborhoods and property values hit hard by foreclosures and vacant buildings.


Also designed to benefit hard-hit areas are the recent establishment of a Cook County Land Bank and legislation waiting for Gov. Pat Quinn's signature that will fast-track the foreclosure process for vacant, abandoned homes while providing financial resources to foreclosure prevention efforts.


mepodmolik@tribune.com


Twitter @mepodmolik





Read More..

Chicago, your commute will likely take far longer than you think









You can predict with a high degree of confidence that the time it takes to drive from Point A to B on any given day is unpredictable.


And it's not just snowy or rainy days. It can be any day.


If there is a bright side, it's that Chicago was not the worst.





Residents of the Chicago area are accommodating that increasing uncertainty by setting aside more time each day — just in case — for the commute, new research shows.


For the most important trips, such as going to work, medical appointments, the airport or making a 5:30 p.m. pickup at the child care center to avoid late fees, drivers in northeastern Illinois and northwest Indiana should count on allotting four times as much time as it would take to travel in free-flowing traffic, according to the "Urban Mobility Report" to be released Tuesday by the Texas A&M Transportation Institute. The analysis is based on 2011 data, which are the most recent available.


It is the first time that travel reliability was measured in the 30-year history of the annual report. The researchers created a Planning Time Index geared toward helping commuters reach their destinations on time in more than 95 percent of the trips. A second index, requiring less padding of travel time, would get an employee to work on time four out of five days a week.


"If you plan only for average traffic conditions on your trip in the Chicago area, you are going to be late at least half the time," said Bill Eisele, a senior research engineer at the Transportation Institute who co-authored the study.


The constant unreliability that hovers over commuting is stealing precious time from other activities, crimping lifestyles, causing mounting frustration for drivers and slapping extra costs on businesses that rely on just-in-time shipments to manage inventory efficiently, researchers found.


The Chicago region ranked No. 7 among very large urban areas and 13th among 498 U.S. cities on a scale of the most unreliable highway travel times. The Washington area was the worst. A driver using the freeway system in the nation's capital and surrounding suburbs should budget almost three hours to complete a high-priority trip that would take only 30 minutes in light traffic, the study said.


The Washington area was followed on the list by the metropolitan areas of Los Angeles, New York-Newark, Boston, Dallas-Fort Worth, and Seattle.


Rounding out the top 10, the Chicago metro area was trailed by San Francisco-Oakland, Atlanta, and Houston.


Truck driver Frank Denk said he usually adds an hour or two to his trip through the Chicago area. Sometimes, it's not enough, other times traffic isn't a problem, he said. The one constant, Denk said Monday afternoon while taking a break at the O'Hare Oasis on the Tri-State Tollway, is that it is almost impossible to anticipate correctly.


"Job-wise, it can be very detrimental to truckers," said Denk, who is based in Green Bay, Wis. "All of a sudden, you're not able to make your delivery."


But quadrupling the time to travel back and forth each day? That's excessive, said Mike Hennigan, a 64-year-old accountant who regularly commutes from his Evanston home to his office near the junction of the Kennedy and Edens expressways. He recommends doubling the anticipated travel time.


"I can predict when it's going to be bad," Hennigan said, although he is less optimistic about his travel times when he heads toward downtown.


"Coming into the Loop can be deadly, especially later in the week," Hennigan said.


Overall, traffic congestion in the Chicago region is getting worse as the economy improves, although it's not as severe as the grip that gridlock has taken recently on some other very large metropolitan areas in the U.S., according to the report. The Washington area again topped the list, followed by Los Angeles, San Francisco-Oakland, New York-Newark, Boston, Houston, Atlanta, Chicago, Philadelphia, and Seattle.


No longer being ranked at the very top of the congestion heap provides little consolation for Chicago-area drivers.


What should be a 20-minute jaunt across town in Chicago or the suburbs if highway capacity were sufficient to permit vehicles to travel the speed limit now becomes about an 80-minute ordeal, according to the Texas A&M study. Scheduling 80 minutes for the trip would ensure an on-time arrival 19 out of 20 times, the study concluded.


But that would be similar to treating every day of the year as if it were like Monday, when a moderate snowfall blanketing the Chicago region smacked traffic into slow motion during the morning rush.





Read More..

NBC Universal reshuffles, Hammer takes over cable networks






(Reuters) – Longtime NBC Universal executive Bonnie Hammer will soon be running all of the media company’s cable networks besides sports and news, as part of a reshuffling, NBC‘s CEO Steve Burke said on Monday.


In a memo to staff, Burke said that starting immediately, Hammer will oversee the entire cable portfolio, including Bravo and Oxygen, which are cable networks previously controlled by Lauren Zalaznick. The new unit, which also includes USA Network, SYFY and E!, will be renamed the cable entertainment group.






Burke said this new division will “represent approximately 50 percent of the company’s operating cash flow.”


In the first three quarters of 2012, NBC generated $ 2.9 billion in operating cash flow. Comcast, which has been the majority owner of NBC since 2011, will report its fourth quarter and full year results on February 13. Cable networks, including sports and news channels overseen by other executives, by far generates the most revenue and profit at NBC Universal.


“I know that with this structure Bonnie and her team will maximize the power and profitability of this portfolio,” Burke said in the memo.


Zalaznick, who will no longer run any cable networks, will become the executive vice president of NBC Universal and will focus on digital initiatives such as “TV Everywhere” as well as “windowing strategies,” which means how soon to make shows available on the Internet after they air on television. She will continue to oversee NBC’s digital assets such as movie ticketing website Fandango.


NBC also said that Joe Uva, a former Univision executive, will become Chairman of Hispanic Enterprises and Content in April, a newly created position. UVA, along with Hammer and Zalaznick will report to Burke.


The moves come a few days after NBC News President Steve Capus said he would be leaving the network after struggles at the unit, including lower ratings for its flagship morning TV show, “Today.”


(This version of the story changes the last word in second paragraph to reflect that new unit name will be “cable entertainment group” and not “cable entertainment business.”)


(Reporting By Liana B. Baker; Editing by Marguerita Choy)


TV News Headlines – Yahoo! News





Title Post: NBC Universal reshuffles, Hammer takes over cable networks
Url Post: http://www.news.fluser.com/nbc-universal-reshuffles-hammer-takes-over-cable-networks/
Link To Post : NBC Universal reshuffles, Hammer takes over cable networks
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

Well: Expressing the Inexpressible

When Kyle Potvin learned she had breast cancer at the age of 41, she tracked the details of her illness and treatment in a journal. But when it came to grappling with issues of mortality, fear and hope, she found that her best outlet was poetry.

How I feared chemo, afraid
It would change me.
It did.
Something dissolved inside me.
Tears began a slow drip;
I cried at the news story
Of a lost boy found in the woods …
At the surprising beauty
Of a bright leaf falling
Like the last strand of hair from my head

Ms. Potvin, now 47 and living in Derry, N.H., recently published “Sound Travels on Water” (Finishing Line Press), a collection of poems about her experience with cancer. And she has organized the Prickly Pear Poetry Project, a series of workshops for cancer patients.

“The creative process can be really healing,” Ms. Potvin said in an interview. “Loss, mortality and even hopefulness were on my mind, and I found that through writing poetry I was able to express some of those concepts in a way that helped me process what I was thinking.”

In April, the National Association for Poetry Therapy, whose members include both medical doctors and therapists, is to hold a conference in Chicago with sessions on using poetry to manage pain and to help adolescents cope with bullying. And this spring, Tasora Books will publish “The Cancer Poetry Project 2,” an anthology of poems written by patients and their loved ones.

Dr. Rafael Campo, an associate professor of medicine at Harvard, says he uses poetry in his practice, offering therapy groups and including poems with the medical forms and educational materials he gives his patients.

“It’s always striking to me how they want to talk about the poems the next time we meet and not the other stuff I give them,” he said. “It’s such a visceral mode of expression. When our bodies betray us in such a profound way, it can be all the more powerful for patients to really use the rhythms of poetry to make sense of what is happening in their bodies.”

On return visits, Dr. Campo’s patients often begin by discussing a poem he gave them — for example, “At the Cancer Clinic,” by Ted Kooser, from his collection “Delights & Shadows” (Copper Canyon Press, 2004), about a nurse holding the door for a slow-moving patient.

How patient she is in the crisp white sails
of her clothes. The sick woman
peers from under her funny knit cap
to watch each foot swing scuffing forward
and take its turn under her weight.
There is no restlessness or impatience
or anger anywhere in sight. Grace
fills the clean mold of this moment
and all the shuffling magazines grow still.

In Ms. Potvin’s case, poems related to her illness were often spurred by mundane moments, like seeing a neighbor out for a nightly walk. Here is “Tumor”:

My neighbor walks
For miles each night.
A mantra drives her, I imagine
As my boys’ chant did
The summer of my own illness:
“Push, Mommy, push.”
Urging me to wind my sore feet
Winch-like on a rented bike
To inch us home.
I couldn’t stop;
Couldn’t leave us
Miles from the end.

Karin Miller, 48, of Minneapolis, turned to poetry 15 years ago when her husband developed testicular cancer at the same time she was pregnant with their first child.

Her husband has since recovered, and Ms. Miller has reviewed thousands of poems by cancer patients and their loved ones to create the “Cancer Poetry Project” anthologies. One poem is “Hymn to a Lost Breast,” by Bonnie Maurer.

Oh let it fly
let it fling
let it flip like a pancake in the air
let it sing: what is the song
of one breast flapping?

Another is “Barn Wish” by Kim Knedler Hewett.

I sit where you can’t see me
Listening to the rustle of papers and pills in the other room,
Wondering if you can hear them.
Let’s go back to the barn, I whisper.
Let’s turn on the TV and watch the Bengals lose.
Let’s eat Bill’s Doughnuts and drink Pepsi.
Anything but this.

Ms. Miller has asked many of her poets to explain why they find poetry healing. “They say it’s the thing that lets them get to the core of how they are feeling,” she said. “It’s the simplicity of poetry, the bare bones of it, that helps them deal with their fears.”


Have you written a poem about cancer? Please share them with us in the comments section below.
Read More..

Boeing asks FAA to allow Dreamliner test flights









Aerospace giant Boeing Co. has asked the Federal Aviation Administration to let it begin test flights on its grounded 787 Dreamliner passenger jet.

The new plane has been grounded since Jan. 16 by the FAA because of numerous incidents and high-profile fires involving the onboard lithium-ion batteries. Investigators around the world are looking into the matter.

The company disclosed its request for in-flight testing Monday in an email.

“Boeing has submitted an application to conduct test flights, and it is currently under evaluation by the FAA,” said Marc Birtel, a company spokesman, who would not comment further.

The FAA is reportedly looking into Boeing request, but would not comment.

The 787's battery systems were called into question Jan. 7 when a smoldering fire was discovered on the underbelly of a Dreamliner in Boston operated by Japan Airlines after the 183 passengers and 11 crew members had deplaned at the gate.

The National Transportation Safety Board is examining what went wrong. On Friday, the NTSB released its seventh update on the investigation into the lithium-ion battery systems. It said it has begun CT scanning the battery cells to examine their internal condition.

In addition, the NTSB disclosed that a battery expert from the Department of Energy joined the investigative team to lend additional expertise to ongoing testing.

In a separate incident Jan. 16 involving a 787 operated by All Nippon Airways in southwestern Japan, smoke was seen swirling from the right side of the cockpit after an emergency landing related to the plane's electrical systems. All 137 passengers and crew members were evacuated from the aircraft and slid down the 787's emergency slides.

The Japan Transport Safety Board, the country's version of the NTSB, is heading the investigation into All Nippon's emergency landing and reported fire.

No passengers or crew members were reported injured in the incidents. But the recent events have become a public relations nightmare for Boeing, which has long heralded the Dreamliner as a forerunner of 21st century air travel.

The 787, a twin-aisle aircraft that can seat 210 to 290 passengers, is the first large commercial jet with more than half its structure made of composite materials rather than aluminum sheets. It's also the first large commercial aircraft that extensively uses electrically powered systems involving lithium-ion batteries.

Boeing's lithium-ion batteries are made in Japan by Kyoto-based GS Yuasa Corp.

ALSO:


British troops use mini-drones to find targets on the battlefield


Airbus snags deal worth $9 billion, including order for 787 rival


Sea Launch mission fails; rocket, Intelsat satellite crash in ocean





Read More..

Ravens stave off 49ers' rally to win Super Bowl 34-31









NEW ORLEANS – The Ravens were almost done in Sunday by a reign delay.

A power outage at the Superdome halted Super Bowl XLVII for 34 minutes casting the stadium into a twilight-like darkness and allowing the reeling 49ers to regroup with almost a full half remaining.






Despite an impressive power surge by the 49ers, however, the Ravens were able to hang on for a 34-31 victory, hoisting the Lombardi Trophy for the second time in their history.

"It's never pretty, it's never perfect, but it's us," said Ravens coach John Harbaugh, whose team had lost four of its last five regular-season games before going on a marvelous run that included knocking off the Colts, Broncos and Patriots to reach the biggest stage.

Even before the ball was kicked off, the game made history. For the first time, brothers stood on opposite sidelines as head coaches. John's younger brother, Jim, coaches the 49ers, making Sunday's victory somewhat bittersweet for the Ravens coach.

"It's tough," John said. "It's very tough. It's a lot tougher than I thought it was going to be. It's very painful."

Most excruciating for the 49ers was how close they came. The game essentially ended on a goal-line stand, with three incomplete passes by the 49ers from the Ravens' 5 inside the final two minutes.

Second-year quarterback Colin Kaepernick, who showed incredible poise for a player with just 10 career starts, failed to connect with Michael Crabtree on three straight tries. On the last, Jim Harbaugh complained angrily that cornerback Jimmy Smith had held Crabtree, but officials were unsympathetic.

"There's no question in my mind that there was a pass interference and then a hold on Crabtree on the last one," the 49ers coach said.

The 49ers are now 5-1 in Super Bowls. By winning, the Ravens improved to 2-0 in the marquee game, becoming the only NFL team with multiple Super Bowl wins and an unblemished record in the big game.

"Lord knows, this season, it was tough, it was rough, I'm just ready to kick my feet up," said an effusive Ravens safety Ed Reed, a New Orleans native who said he felt like leading a parade "all the way up Poydras," the street that runs past the Superdome.

Reed intercepted an overthrown Kaepernick pass in the first half and grabbed a piece of history. It was the first time a 49ers quarterback had been picked off in the Super Bowl, with Joe Montana and Steve Young accounting for 17 touchdown passes in the previous five appearances.

Kaepernick completed 16 of 28 for 302 yards, with a touchdown and an interception. He also ran seven times for 62 yards and a score.

The star quarterback Sunday was Ravens quarterback Joe Flacco, who threw three touchdown passes and was named the game's most valuable player.

"I think we gave the country a pretty good game to watch — not to our liking necessarily — but that's the way it goes sometimes, and that's the way we do things," said Flacco, who completed 22 of 33 for 287 yards with a passer rating of 124.2.

The game was a masterpiece for the Ravens' Jacoby Jones, who grew up in New Orleans.

First, he had a 56-yard touchdown in the second quarter that had to have countless fans rewinding their DVRs. He slipped past cornerback Chris Culliver and caught a slightly underthrown bomb, turning with his back to the goal line to grab the ball, then falling to the ground. Untouched, he immediately popped to his feet, spun away from a defender, then beat Culliver again to the end zone.

That was just one of Culliver's travails on a very bad night for the young corner, who found himself in hot water earlier in the week when he said on a radio show that he would never accept a gay teammate.

Keeping up with Jones wasn't an option, not after he took the opening kickoff of the second half and returned it 108 yards for a touchdown, setting a Super Bowl record and tying the NFL record. Jones' return took a mere 11 seconds. Not bad for a guy in pads who had to dodge defenders along the way.

Before most of the lights ringing the field went out, the Ravens had built a 28-6 lead. But after the delay, during which players stretched in the surreal half-light, the 49ers answered with a 23-3 run.

With their red-and-gold-clad fans roaring their approval, the 49ers just missed a chance to forge a tie at 31 with 10:04 remaining, after Kaepernick ran for a 15-yard touchdown, the longest scoring run by a quarterback in Super Bowl history. But his conversion pass to Randy Moss was incomplete, however, leaving the Ravens to cling to a tenuous two-point lead.

The 49ers wouldn't score on offense again, and their only points came on an intentional safety by the Ravens in the game's final moments.

The game was a curtain-dropper for All-Pro Ravens linebacker Ray Lewis, who punctuated his career the way NFL stars John Elway, Jerome Bettis and Michael Strahan did — with a championship ring.

For the Ravens, the night was unforgettable.

Asked what he told his team before the game, John Harbaugh said: "I told them there's an old Motown song that says, 'There ain't no mountain high enough, ain't no valley low enough, ain't no river wide enough to keep us from winning this championship.' That's exactly what I said. It's a great song too."

Reed had another ditty in mind.

The All-Pro safety, having collected the crowning achievement of his storied career, cleared his throat, leaned into his microphone and crooned: "I've got two tickets to paradise …"

It was that kind of night.

sfarmer@tribune.com



Read More..

Looks Like Alicia Keys Will Play Piano During Super Bowl National Anthem






Alicia Keys woke up on Super Bowl Sunday and apparently had the urge to tweet, sharing a rehearsal photo of herself behind a piano in an empty Mercedes-Benz Superdome.


Keys, who was just named Blackberry’s global creative director, will sing “The Star-Spangled Banner” before kickoff and the photo suggests she’ll do so while playing piano.






[More from Mashable: Super Bowl 2013 Commercials: Watch Them All Here]


If Keys does pound the keys tonight, she will be the first musician to do so during a Super Bowl national anthem performance since Billy Joel in 2007 (see video in gallery below).


Update: Keys also tweeted the red dress she’ll wear during her performance.


[More from Mashable: Beyonce’s Super Bowl Show in 10 Fierce Photos]


Kelly Clarkson sang the national anthem in 2012, a year after Christina Aguilera flubbed the song’s lyrics at the previous Super Bowl (watch below). Other past performers include Whitney Houston, Garth Brooks, Mariah Carey, Faith Hill, Neil Diamond, Diana Ross, Jewel, Harry Connick Jr., Dixie Chicks and Cher.


Keys, a 14-time Grammy winner, will embark on a North American concert tour in March. Her fifth studio album, Girl on Fire, debuted atop the Billboard 200 albums chart in November.


Keys is set to perform the national anthem at 6:30 p.m. ET on CBS.



Click here to view the gallery: Previous National Anthem Singers at the Super Bowl


Image via Pascal Le Segretain/Getty Images


This story originally published on Mashable here.


Tech News Headlines – Yahoo! News





Title Post: Looks Like Alicia Keys Will Play Piano During Super Bowl National Anthem
Url Post: http://www.news.fluser.com/looks-like-alicia-keys-will-play-piano-during-super-bowl-national-anthem/
Link To Post : Looks Like Alicia Keys Will Play Piano During Super Bowl National Anthem
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

Beyonce electrifies at Super Bowl halftime show






If naysayers still doubted Beyonce‘s singing talents — even after her national anthem performance this week at a press conference — the singer proved she is an exceptional performer at the Super Bowl halftime show.


Beyonce opened and closed her set belting songs, and in between she danced hard and heavy — and better than most contemporary pop stars.






She set a serious tone as she emerged onstage in all black, singing lines from her R&B hit “Love on Top.” The stage was dark as fire and lights burst from the sides. Then she went into her hit “Crazy In Love,” bringing some feminine spirit to the Superdome as she and her background dancers did the singer’s signature booty-shaking dance. Beyonce ripped off part of her shirt and skirt. She even blew a kiss. She was ready to rock, and she did so like a pro.


Her confidence — and voice — grew as she worked the stage with and without her Destiny’s Child band mates during her 13-minute set, which comes days after she admitted she sang to a pre-recorded track at President Barack Obama‘s inauguration less than two weeks ago.


Beyonce proved not only that she can sing, but that she can also entertain on a stage as big as the Super Bowl’s. The 31-year-old was far better than Madonna, who sang to a backing track last year, and miles ahead of the Black Eyed Peas’ disastrous set in 2011.


Beyonce was best when she finished her set with “Halo.” She asked the crowd to put their hands toward her as she sang the slow groove on bended knee — and that’s when she the performance hit its high note.


“Thank you for this moment,” she told the crowd. “God bless y’all.”


Her background singers helped out as Beyonce danced around the stage throughout most of her performance. There was a backing track to help fill in when Beyonce wasn’t singing — and there were long stretches when she let it play as she performed elaborate dance moves.


She had a swarm of background dancers and band members spread throughout the stage, along with videotaped images of herself dancing that may have unintentionally played on the live-or-taped question. And the crowd got bigger when she was joined by her Destiny’s Child band mates.


Kelly Rowland and Michelle Williams popped up from below the stage to sing “Bootylicious.” They were in similar outfits, singing and dancing closely as they harmonized. But Rowland and Williams were barely heard when the group sang “Independent Woman,” as their voices faded into the background.


They also joined in for some of “Single Ladies (Put a Ring On It),” where Beyonce‘s voice grew stronger. That song featured Beyonce‘s skilled choreography, as did “End of Time” and “Baby Boy,” which also showcased Beyonce‘s all-female band, balancing out the testosterone levels on the football field.


Before the game, Alicia Keys performed a lounge-y, piano-tinged version of the national anthem that her publicist assured was live. The Grammy-winning singer played the piano as she sang “The Star Spangled Banner” in a long red dress with her eyes shut.


She followed Jennifer Hudson, who sang “America the Beautiful” with the 26-member Sandy Hook Elementary School chorus. It was an emotional performance that had some players on the sideline on the verge of tears. Hudson also sang live, her publicist said.


The students wore green ribbons on their shirts in honor of the 20 first-graders and six adults who were killed in a Dec. 14 shooting rampage at the school in Newton, Conn.


The students began the song softly before Hudson, whose mother, brother and 7-year-old nephew were shot to death five years ago, jumped in with her gospel-flavored vocals. She stood still in black and white as the students moved to the left and right, singing background.


___


Follow Mesfin Fekadu on Twitter at http://twitter.com/MusicMesfin


Entertainment News Headlines – Yahoo! News





Title Post: Beyonce electrifies at Super Bowl halftime show
Url Post: http://www.news.fluser.com/beyonce-electrifies-at-super-bowl-halftime-show/
Link To Post : Beyonce electrifies at Super Bowl halftime show
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

Medicines Co. Licenses Rights to Cholesterol Drug



The drug, known as ALN-PCS, inhibits a protein in the body known as PCSK9. Such drugs might one day be used to treat millions of people who do not achieve sufficient cholesterol-lowering from commonly used statins, such as Lipitor.


The Medicines Company will pay $25 million initially and as much as $180 million later if certain development and sales goals are met, under the deal expected to be formally announced Monday. It will also pay Alnylam, which is based in Cambridge, Mass., double-digit royalties on global sales.


That is small payment for a drug with presumably a huge potential market, probably reflecting that Alnylam is still in the first of three phases of clinical trials, well behind some far bigger competitors.


The team of Sanofi and Regeneron Pharmaceuticals is already entering the third and final stage of trials with their PCSK9 inhibitor, as is Amgen. Pfizer and Roche are in midstage trials.


ALN-PCS is different from the other drugs. It uses a gene-silencing mechanism called RNA interference, aimed at shutting off production of the PCSK9 protein. The other drugs are proteins called monoclonal antibodies that inhibit the action of PCSK9 after it has been formed.


Alnylam and the Medicines Company hope that turning off the faucet, as it were, will be more efficient than mopping the floor, allowing their drug to be given less frequently and in smaller amounts.


But that has yet to be proved. No drug using RNA interference has reached the market.


The Medicines Company, based in Parsippany, N.J., generates almost all of its revenue from one product — Angiomax, an anticlotting drug used when patients receive stents to open clogged arteries.


Dr. Clive A. Meanwell, chief executive of the company, said that PCSK9 inhibitors are likely to be used at first mainly by patients with severe lipid problems under the care of interventional cardiologists, the same doctors who use Angiomax. “It really is quite adjacent to what we do,” he said.


The Medicines Company licensed Angiomax from Biogen Idec, where the drug was invented and initially developed under a team led by Dr. John M. Maraganore, who is now the chief executive of Alnylam.


“It’s a bit like getting the band back together,” Dr. Maraganore said.


Read More..

Battle between Cubs, rooftop owners is best viewed from sidelines








From the Super Bowl to the sandlot, just as surely as players give 110 percent, the math of sports is always suspect.


Sports isn't like other businesses. What other investment becomes more attractive because of its unpredictability? Revenue can always be accounted for, but what of ego, pride, loyalty, stubbornness or even the microns that separate a catch from a muff?


In no other industry does a perennial also-ran continue to see its value increase.






That's why it's a mistake to get too wrapped up in the dispute between the wealthy Ricketts family that owns the Chicago Cubs and the owners of buildings adjacent to Wrigley Field who have turned their rooftops into garish, outsize extensions of the bleachers?


If it's just money, there's a price — and if there's a price, there's a solution to be worked out. If it's a game, the drama is best enjoyed with healthy detachment because logic may or may not dictate the outcome.


Like a hockey fight, one or both combatants will eventually run out of gas, then will be penalized with the loss of time and opportunity.


"What we are trying to do is resolve this right now," Jim Lourgos, one of the rooftop club owners, said recently during a visit to Tribune Tower. "If you're in court on something like this, my feeling has always been that by the time you're in court, you've already lost."


Unless, say, you're trying to run out the clock. But enough with the sports metaphors.


At the center of this dispute, for those late arrivals to this fight, is a nearly 99-year-old ballpark long overdue for a rehab. Wrigley must be brought into the 21st century, in the interest of the team but also all those who benefit from its standing as a tourist magnet, including those peddling rooftop seats.


The Ricketts family is said to finally have abandoned its quest for taxpayer help in funding the project.


It is true other sports franchises in town have received taxpayer help to build facilities that enrich their owners, but every bad idea has to end somewhere. This would at last be consistent with the philosophy of patriarch Joe Ricketts, who has said he considers it "a crime for our elected officials to borrow money today to spend money today and push the repayment of that loan out into the future on people who aren't even born yet."


Rather than hitting up the cash-strapped city and state, the Ricketts clan instead wants help in the form of concessions such as a relaxation of landmark restrictions and city ordinances that limit such matters as the number of night games and ads in the ballpark. They also want to turn one of the streets into a pedestrian mall.


The rooftop interests, which kick 17 percent of their revenue back to the Cubs as part of a nine-year-old settlement with the team, are terrified the loosened restrictions will result in their views of the ballpark being blocked by advertising signs.


Never mind that Wrigley Field itself has many seats with obstructed views, thanks to support posts.


The rooftoppers have offered to put advertising on their building facades with the money going to the team and city. And they think they have leverage via the 2004 contract they signed with then-Cubs owner Tribune Co. (Yes, that's the same Tribune Co. that owns the Chicago Tribune and still has a small piece of the ballclub.) They think they can parlay this into an extension of their current agreement with the team to 2023.


But the contract allows that "any expansion of Wrigley Field approved by governmental authorities shall not be a violation" of the deal, which means if Mayor Rahm Emanuel gets behind the Ricketts, look out.


Rooftop owners talk about the taxes they pay, the people they employ, the money they've invested to make their businesses safe and viable, the character they add to the neighborhood.


The basic argument, however, still seems a little like when your neighbor with the big-screen TV decides to start watching with the drapes closed on what's become movie night at your house. It's bad form to complain that they not only shouldn't shut the drapes but should open the window and turn up the volume so you and the people in your living room you've charged $1 a head can make out the dialogue better.


At the same time it's hard to sympathize with the Ricketts family, which invested $850 million to acquire the team and ballpark, effectively creating a family trust that's a tax-efficient structure for protecting and eventually distributing wealth across generations. It's not as though these people didn't know Wrigley Field was in need of work or the deals in place with the rooftop clubs. They ought to be able to come up with the cash to make this happen, with or without advertising.


That deal is really something, though. For example, the contract calls for the Cubs to help hype them in a variety of ways, advancing the argument that the rooftop clubs are part of the appeal of Wrigley.


There's a requirement that "WGN-TV will show and comment upon the Rooftops' facilities during the broadcasts of Cubs games and the Cubs will request other Cubs television broadcasting partners to do the same." There's also a mandate for the team to "include a discussion about the Rooftops on their tour of Wrigley Field" and to include stories positive about the Rooftops in The Vine Line," the team's publication.


What you won't read in The Vine Line is that this fight, like the ballpark itself, is a fight over something that may increasingly be quaint in the coming decades. The Los Angeles Dodgers last week announced a $7 billion, 25-year deal for their own cable channel, following the example of the New York Yankees, which already have their own.


With that kind of money coming in via television, the pressure to make money from ticket sales may be relieved somewhat, turning the stadiums into glorified studios. But that may be too logical for sports. For one thing, it assumes that player salaries won't escalate in response as owners ditch their budgets in order to get an edge that may or may not materialize.


That's the thing about sports. You never know how the numbers will add up.


philrosenthal@tribune.com


Twitter @phil_rosenthal






Read More..